The second season picks up where the first left off, with Anne-Marie Duff (Bad Sisters, The Salisbury Poisonings) returning as Dr Susannah Newman, now on a desperate quest to track down a self-confessed serial killer before he kills again that night. When a mysterious new client Jon (Dominic Cooper) admits under hypnosis that he is a murderer and intends on killing another young female that evening, Susannah knows he must be stopped at all costs. 　　When he escapes before the police arrive and as her former lover Detective Superintendent Richard Grove (Ben Miller; Professor T, Paddington 2) is refusing to take action, Susannah is forced to embark on her own deadly mission to save Sapphire’s life, the way she couldn’t do with her own daughter.

韩国闹市街头，生活着一名沉默寡言、逆来顺受的男人池东哲（孔侑 饰）。他从事代驾工作，见惯了他人的白眼和凌辱。真正的他是从北朝鲜逃过来的前特殊部队成员，为了追查害死妻儿的凶手而甘愿抛弃一切。在朝鲜他得到了德高望重的朴会长的器重，谁知会长在某个夜晚被人杀害，老人临死前将自己 的眼镜交给东哲。成为此案重要嫌疑人的东哲卷入了一连串充满杀戮和阴谋的漩涡，更不知道那副眼镜中竟然隐藏着天大的秘密。朝鲜秘密部门蠢蠢欲动，空军特殊部队CCT的训练教官闵世勋大校（朴熙顺 饰）也对东哲紧追不舍。 　　站在风口浪尖的东哲，被迫凭借一己之力周旋在各方势力之中……

乔医生看似有着完美的生活：他拥有忠诚的妻子和可爱的女儿，作为临床心理学家事业有成。不仅如此，他还因救下了一名打算自杀的病人，而成为网络上人人讨论的英雄。不过，乔医生似乎没有他呈现出来的那样简单。